Apache webserver with nginx proxy throwing (110: Connection timed out)

I need help with this issue, at times randomly on my site i get Error 504, with cloudflare saying Gateway Timed out.

Here is the log.

Code: [Select]

/usr/local/apache/domlogs/DOMAIN.com.error.log:1456574:2020/05/16 00:39:41 [error] 2729#2729: *46672 upstream timed out (110: Connection timed out) while connecting to upstream, client: MY-IP, server: DOMAIN.com, request: "GET /live/sport5mobile/ HTTP/1.1", upstream: "http://DOMAIN:8181/live/sport5mobile/", host: "www.DOMAIN.com", referrer: "https://www.DOMAIN.com/live/mtv/"
It says port 8181, which has apache running