Cannot read/send mail with Microsoft Live Mail, Roundcube mail working for read

Hi
Hope this makes sense, I can view email etc (cannot send) with roundcube webmail. But no mail is being received using Microsoft LiveMail or Thunderbird, No error appears in these when checking for mail. if I try to send mail I then get an error.

The message could not be sent. The setting for your outgoing email [SMTP] server might need to be configured. To find the server settings for '######@yahoo.com', please contact your email service provider.

Server Error: 550
Server Response: 550 Administrative prohibition
Protocol: SMTP
Port: 25
Secure(SSL): No


Any thoughts appreciated.

IDC

usually, email servis working out of the box, just make sure port 25 not blocked by you Internet/VPS/Dedi provider..