Problem to sent E-Mail (450 4.1.1 : Recipient address rejected)

This is my error-message in the Mail Queue Manager:

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8B59B660B9 - 633 Thu Jul 14 06:17:59  admin@*****.de

(host 127.0.0.1[127.0.0.1] said: 451 4.5.0 Error in processing, id=21476-02, quar+notif FAILED: temporarily unable to notify admin:
450 4.1.1 from MTA(smtp:[127.0.0.1]:10025): 450 4.1.1 : Recipient address rejected: User unknown in virtual mailbox table at /usr/sbin/amavisd line 15808.
(in reply to end of DATA command))

pawel.gralla@*****-*****.de

Is the problem with Clamd related? Because Clamd (ClamAV) is not running, because when i try to start i see this error:

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Starting Clam AntiVirus Daemon: LibClamAV Warning: **************************************************
LibClamAV Warning: ***  The virus database is older than 7 days!  ***
LibClamAV Warning: ***   Please update it as soon as possible.    ***
LibClamAV Warning: **************************************************
LibClamAV Error: Can't load /var/lib/clamav/main.cvd: Can't verify database integrity
LibClamAV Error: cli_loaddbdir(): error loading database /var/lib/clamav/main.cvd
ERROR: Can't verify database integrity
[FAILED]

Ok i have fixed the Problem.


when I send one E-Mail from Roundcube, clamd shows me this message in the dashboard:

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clamd dead but subsys locked when i reboot the server then solves the problem.


a bigger Problem is that I can send emails but not receive.