Yes. When I look at the mail logo, non-existent mails on my server are constantly sending mail.
mail log:
cbpolicyd[3094]: module=Quotas, action=defer, host=185.208.23.255, helo=255.23.208.185.dynamic.electronicamartinez.es, from=ferdinand@he.com, to=ferdinand@he.com, reason=quota_match, policy=9, quota=6, limit=7, track=Sender:@he.com, counter=MessageCount, quota=51.66/50 (103.3%)