[proxy_fcgi:error] AH01071

Mostof my sites are working fine. But one of the sites throughs this error

[proxy_fcgi:error] [pid 107694:tid 107699] [client 46.243.3.42:58152] AH01071: Got error 'Primary script unknown'

If I reboot server, sites works again for few hours

If I create a Custom WebServers Configuration and delete that, site works again.

Please suggest

Looks like the issue is due to infection discussed here

https://forum.centos-webpanel.com/centos-webpanel-bugs/critical-multiple-cwp-servers-infected-arbitrary-php-code-execution-via-publ/